RNAlib-2.2.7
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This module covers functions that enable the incorporation of ligand binding free energies to specific hairpin/interior loop motifs by means of generic soft constraints. More...
Files | |
file | ligand.h |
Functions for incorporation of ligands binding to haipirn and interior loop motifs. | |
Functions | |
int | vrna_sc_add_hi_motif (vrna_fold_compound_t *vc, const char *seq, const char *structure, FLT_OR_DBL energy, unsigned int options) |
Add soft constraints for hairpin or interior loop binding motif. More... | |
This module covers functions that enable the incorporation of ligand binding free energies to specific hairpin/interior loop motifs by means of generic soft constraints.
int vrna_sc_add_hi_motif | ( | vrna_fold_compound_t * | vc, |
const char * | seq, | ||
const char * | structure, | ||
FLT_OR_DBL | energy, | ||
unsigned int | options | ||
) |
#include <ViennaRNA/ligand.h>
Add soft constraints for hairpin or interior loop binding motif.
Here is an example that adds a theophylline binding motif. Free energy contribution is derived from , taken from Jenison et al. 1994
vc | The vrna_fold_compound_t the motif is applied to |
seq | The sequence motif (may be interspaced by '&' character |
structure | The structure motif (may be interspaced by '&' character |
energy | The free energy of the motif (e.g. binding free energy) |
options | Options |