Metagenomics Longitudinal Differential Abundance Method

Documentation for package ‘MetaLonDA’ version 1.1.0

areaPermutation	Calculate Area Ratio (AR) of each feature's time interval for all permutations
curveFitting	Fit longitudinal data
findSigInterval	Find significant time intervals
intervalArea	Calculate Area Ratio (AR) of each feature's time interval
metalonda	Metagenomic Longitudinal Differential Abundance Analysis for one feature
metalondaAll	Metagenomic Longitudinal Differential Abundance Analysis for all Features
metalonda_test_data	Simulated data of OTU abundance for 2 phenotypes each has 5 subjects at 10 time-points
normalize	Normalize count matrix
permutation	Permute group labels
visualizeArea	Visualize significant time interval
visualizeARHistogram	Visualize Area Ratio (AR) empirical distribution
visualizeFeature	Visualize Longitudinal Feature
visualizeFeatureSpline	Visualize the feature trajectory with the fitted Splines
visualizeTimeIntervals	Visualize all significant time intervals for all tested features