BayesPrism: Bayesian cell type and gene expression deconvolution


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Documentation for package ‘BayesPrism’ version 2.0

Help Pages

cleanup.genes A function to filter genes by gene category and to exlcude lowly expressed genes.
collapse Summing up reads across cells from each cell type/state
get.exp Extract results from the BayesPrism object
get.exp.stat The function to perform differential expression test for the selection of marker genes.
get.fraction Extract results from the BayesPrism object
learn.embedding Embedding learning
learn.embedding.nmf Embedding learning
new.prism Construct a prism object
plot.bulk.outlier Visualize and determine outliers from the bulk mixture
plot.bulk.vs.sc Make the bulk vs scRNA scatter plot by gene type (coding, lncRNA and psuedogenes)
plot.cor.phi Plot correlation matrix for the reference profile phi
plot.scRNA.outlier Visualize and determine outliers in scRNA-seq reference
run.prism Main function to Run BayesPrism
select.gene.type A function to select genes by gene type (e.g. "protein_coding", "pseudogene", "lincRNA" ).
select.marker The function to perform differential expression test for the selection of marker genes.
update.theta Update cell type fraction using output from the initial Gibbs sampling