Oscope - A statistical pipeline for identifying oscillatory genes in unsynchronized single cell RNA-seq


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Documentation for package ‘Oscope’ version 1.10.0

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Oscope-package Oscope - A statistical pipeline for identifying oscillatory genes in unsynchronized single cell RNA-seq
AbsCor Calculate absolute correlations among gene pairs
CalcMV Calculate estimated mean and variance of RNA-Seq data
FlagCluster Flag gene clusters with small within-cluster phase differences and/or small within-cluster sine scores
FormatSineOut Format SinFun outputs from lists to matrix
ImpShift Search for the optimal sample order by using the Extended Nearest Insertion
NISFun Run Extended Nearest Insertion and 2-opt on a gene cluster identified by OscopeKM function
NormForSine Rescale the gene/isoform expression matrix
Opt2Shift Run the 2-opt algorithm to improve the optimal order searching of the Extended Nearest Insertion
Oscope Oscope - A statistical pipeline for identifying oscillatory genes in unsynchronized single cell RNA-seq
OscopeENI Search for the optimal sample order for different gene clusters
OscopeExampleData Simulated gene level data set with 600 genes and 30 cells.
OscopeKM Oscope K medoid module
OscopeSine Apply sine model on the full set of genes or isoforms
PermuCut Define sine scroe cutoff using permuted data
PipeR Calculate residual of polynomial fit
PipeShiftCDF Calculate residual of the sliding polynomial regression
scanK Run k-medoid algorithm with varying k on similarity matrix
SineFun Apply sine model on one particular gene vs. other genes
SineOptim Function for searching optimal phase shift