LiP Significance Analysis in shotgun mass spectrometry-based proteomic experiments


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Documentation for package ‘MSstatsLiP’ version 1.0.0

Help Pages

annotSite Annotate modification site
BarcodePlotLiP Barcode plot. Shows protein coverge of LiP modified peptides.
calculateTrypticity Calculates level of trypticity for a list of LiP Peptides.
correlationPlotLiP Plot run correlation for provided LiP and TrP experiment.
dataProcessPlotsLiP Visualization for explanatory data analysis
dataSummarizationLiP Summarizes LiP and TrP datasets seperately using methods from MSstats.
groupComparisonLiP Model LiP and TrP data and make adjustments if needed Returns list of three modeled datasets
groupComparisonPlotsLiP Visualization for model-based analysis and summarization
LiPRawData LiPRawData
locateMod Locate modified sites with a peptide
locatePTM Annotate modified sites with associated peptides
MSstatsLiP MSstatsLiP: A package for identifying and analyzing changes in protein structures caused by compound binding in cellur lysates.
MSstatsLiP_data MSstatsLiP_data
MSstatsLiP_model MSstatsLiP_model
MSstatsLiP_Summarized MSstatsLiP_Summarized
PCAPlotLiP Visualize PCA analysis for LiP and TrP datasets.
SkylineTest SkylineTest
SkylinetoMSstatsLiPFormat Converts raw LiP MS data from Skyline into the format needed for MSstatsLiP.
SpectronauttoMSstatsLiPFormat Converts raw LiP MS data from Spectronautt into the format needed for MSstatsLiP.
tidyFasta Read and tidy a FASTA file
TrPRawData TrPRawData
trypticHistogramLiP Histogram of Half vs Fully tryptic peptides. Calculates proteotypicity, and then uses calcualtions in histogram.