Single-cell RNA sequencing data normalization


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Documentation for package ‘bayNorm’ version 1.0.6

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AdjustSIZE_fun Adjust MME size estimate
bayNorm A wrapper function of prior estimation and bayNorm function
bayNorm_sup bayNorm with estimated parameters as input
BB_Fun Estimating size for each gene by either 1D or 2D maximization of marginal distribution
BetaFun Estimate capture efficiency for cells
DownSampling Binomial downsampling
EstPrior Estimate size and mu for Negative Binomial distribution for each gene using MME method
EXAMPLE_DATA_list A subset of Grun et al (2014) data: 2i samples
NOISY_FUN Noisy gene detection
noisy_gene_detection A wrapper function for noisy gene detection from raw data. his produces synthetic control, performs bayNorm on both real cell data and synthetic controls and does noisy gene detection.
Prior_fun A wrapper function of 'EstPrior' and 'AdjustSIZE_fun'
SyntheticControl Generate synthetic control